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PRINTS and its automatic supplement, prePRINTS.

T K Attwood1, P Bradley, D R Flower

  • 1School of Biological Sciences and Department of Computer Science, The University of Manchester, Manchester M13 9PT, UK. attwood@bioinf.man.ac.uk

Nucleic Acids Research
|January 10, 2003
PubMed
Summary
This summary is machine-generated.

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The PRINTS database provides protein fingerprints for identifying protein families and functions. An automated supplement, prePRINTS, enhances resource coverage and reduces manual maintenance efforts.

Area of Science:

  • Bioinformatics
  • Proteomics
  • Computational Biology

Background:

  • The Protein-Retentive Interactive Network Database (PRINTS) is a curated resource of protein fingerprints.
  • Protein fingerprints are crucial for classifying uncharacterized protein sequences into known families and inferring potential functions.

Purpose of the Study:

  • To report the September 2002 release (version 36.0) of the PRINTS database.
  • To introduce prePRINTS, an automated supplement designed to expand the database's coverage and streamline maintenance.

Main Methods:

  • The PRINTS database version 36.0 contains 1800 fingerprints, representing approximately 11,000 motifs.
  • The development of an automatic supplement, prePRINTS, was implemented to enhance resource coverage.

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Main Results:

  • The PRINTS database covers a diverse range of proteins, including globular, membrane, and modular polypeptides.
  • The prePRINTS system automates the addition of new fingerprints, increasing the overall coverage of the resource.

Conclusions:

  • The PRINTS database continues to grow steadily, offering a valuable resource for protein sequence analysis.
  • The integration of prePRINTS aims to improve the efficiency and scope of the PRINTS database for researchers.