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Stereospecific synthesis of azetidine-cis-2,3-dicarboxylic acid

Yasushi Arakawa¹, Tomoaki Murakami, Yukimi Arakawa

¹Faculty of Pharmaceutical Sciences, Hokuriku University, Kanazawa, Japan. ya-arakawa@hokuriku-u.ac.jp

Chemical & Pharmaceutical Bulletin

|January 10, 2003

Abstract:

Electrocyclic reaction product of 1-(methoxycarbonyl)-1,2-dihydropyridine was stereospecifically converted by RuO(4) oxidation into azetidine-cis-2,3-dicarboxylic acid.

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