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Effect of physical exercise on lipid metabolism in the elderly
Manuel Teixeira Veríssimo1, António Aragão, Ana Sousa
1Serviço de Medicina I dos Hospitais da Universidade de Coimbra, Coimbra. rjv@esoterica.pt
Purpose:
To assess the effect of regular physical exercise on plasma lipids and apoproteins in an elderly group.
Material And Methods:
Sixty-three old people of both sexes, aged between 65 and 94, were randomly distributed between a test group (n = 31) and a control group (n = 32). The test group followed a program of physical exercise for eight months, with intensity of 60% to 80% of heart rate reserve, consisting of three weekly sessions, on alternate days, of 60 minutes each. Before the beginning of the program and eight months afterwards, blood samples were collected to assess total cholesterol, triglycerides, HDL-C, HDL2-C. HDL3-C, apo A1, apo B-100 and apo (a). The ratios total cholesterol/HDL-C, LDL-C/HDL-C, HDL2-C/HDL3-C and apo A1/apo B-100 were also calculated.
Results:
In the test group total cholesterol, triglycerides, LDL-C, apo B-100, total cholesterol/HDL-C and LDL-C/HDL-C decreased significantly; HDL-C, HDL2-C, apo A1, HDL2-C/HDL3-C and apo A1/apo B-100 increased significantly; HDL3-C and apo (a) did not change. The control group did not present any significant alterations in any of the parameters assessed.
Conclusions:
Regular physical exercise decreases vascular risk and may help to reduce cardiovascular events in the elderly.