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[Calicivirus and acute gastroenteritis].

Kirsti Vainio1, Nils Grude

  • 1Smitteverndivisjonen Nasjonalt folkehelseinstitutt Postboks 4404 Nydalen 0403 Oslo. kirsti.vainio@fhi.no

Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke
|January 14, 2003
PubMed
Summary

Calicivirus gastroenteritis outbreaks are common in institutions. Early sample collection within 48-72 hours of symptom onset significantly increases virus detection rates for better control.

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Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Context:

  • Calicivirus gastroenteritis outbreaks frequently occur in institutional settings, particularly affecting the elderly.
  • Controlling these outbreaks is challenging and can lead to ward closures.
  • Accurate diagnostic methods are crucial for effective management.

Purpose:

  • To investigate the prevalence of calicivirus in suspected gastroenteritis cases during the winter season.
  • To evaluate the effectiveness of diagnostic methods for calicivirus detection.

Summary:

  • A study examined 117 fecal samples for calicivirus using nested RT-PCR during the 2001-2002 winter season.
  • Calicivirus was confirmed in 9 out of 16 observed outbreaks.
  • The virus was detected in 21% of analyzed samples, with higher detection rates when samples were collected within the first two days of symptom onset.

Impact:

  • Highlights the need for robust surveillance systems to manage institutional calicivirus outbreaks.
  • Emphasizes the importance of timely specimen collection (within 48-72 hours of illness onset) for accurate laboratory diagnosis.

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