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Changes in cerebral oxygenation in children undergoing surgical repair of ventricular septal defects
Y Morimoto1, Y Niida, K Hisano
1Department of Anaesthesiology and Critical Care Medicine, Hokkaido University Graduate School of Medicine, N15 W7, Kita-ku, Sapporo 0608638, Japan.
Insights
Near-infrared spectroscopy monitoring during pediatric heart surgery revealed significant decreases in oxyhemoglobin during cardiopulmonary bypass. This technique may aid clinical monitoring for ventricular septal defect repair.
Area of Science:
- Cardiology
- Neuroscience
- Medical Technology
Background:
- Limited research exists on cerebral oxygenation changes during pediatric cardiac surgery using conventional near-infrared spectroscopy (NIRS).
- Ventricular septal defects (VSDs) are common congenital heart abnormalities requiring surgical intervention.
Purpose of the Study:
- To investigate changes in cerebral oxygenation during pediatric cardiac surgery for VSD repair using conventional NIRS.
- To assess the clinical utility of NIRS in monitoring brain oxygenation during this procedure.
Main Methods:
- A study was conducted on 16 children undergoing surgical repair of ventricular septal defects.
- Cerebral oxygenation was monitored using conventional near-infrared spectroscopy throughout the surgery.
Main Results:
- Fifteen patients exhibited a consistent pattern: significant decreases in brain tissue oxyhemoglobin during cardiopulmonary bypass, with no significant change in deoxyhemoglobin.
- One patient with reduced lower body blood flow showed a different oxygenation pattern and experienced postoperative complications.
Conclusions:
- Conventional near-infrared spectroscopy demonstrates potential as a valuable tool for clinical monitoring during ventricular septal defect repair.
- Monitoring cerebral oxygenation may help identify patients at risk for adverse outcomes.
Abstract:
There have been few published studies on changes in cerebral oxygenation during paediatric cardiac surgery as measured by conventional near-infrared spectroscopy. We studied changes in cerebral oxygenation in 16 children undergoing surgical repair of ventricular septal defects. Fifteen of the patients showed similar patterns of changes: brain tissue concentrations of oxyhaemoglobin decreased significantly during cardiopulmonary bypass, whereas there was no significant change in brain tissue concentrations of deoxyhaemoglobin. In the remaining patient, who suffered decreased blood flow to the lower body during surgery, the pattern of changes was different to that of the other subjects. This patient suffered postoperative respiratory and renal failure. This study suggests that conventional near-infrared spectroscopy may be useful for clinical monitoring during ventricular septal defect repair.
