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Outcome for donors and recipients in two egg-sharing policies
Efstratios M Kolibianakis1, Herman Tournaye, Kaan Osmanagaoglu
1Center for Reproductive Medicine, Dutch-Speaking Brussels Free University, Brussels, Belgium. stratis@easynet.be
Objective:
To assess the effect of two different donation policies on results of egg-sharing.
Design:
Retrospective analysis.
Setting:
Tertiary referral center.
Patient(S):
One hundred five donor-recipient pairs participating in an egg-sharing program between 1998 and 2001.
Intervention(S):
Egg-sharing was performed according to policy A (retrieval of at least 12 oocytes, with more oocytes allocated to the donor) or policy B (retrieval of at least 8 oocytes, with equal distribution of oocytes between donors and recipients).
Main Outcome Measure(S):
Delivery rate and cycle cancellation rate.
Result(S):
Policy B resulted in a decreased cycle cancellation rate in the recipient group compared with policy A (9.7% vs. 29.7%, respectively; P
Conclusion(S):
Decreasing the number of oocytes required to perform egg sharing from 12 to 8 and dividing the oocytes equally between donors and recipients significantly reduces the cycle cancellation rate while it does not appear to affect adversely the probability of delivery.