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The use of cast gold restorations: scientific basis and clinical technique

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  • 1University of Medicine and Dentistry of New Jersey, USA.

Dentistry Today
|January 15, 2003
PubMed

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Immunoelectron microscopy utilizes immunogold labeling of endogenous proteins with specific antibodies to detect and localize these proteins in cells and tissues. The procedure provides insights into the distribution and quantification of protein under different stimulation conditions offering clues about their functions. Conjugating highly electron-dense gold particles with primary or secondary antibodies allow antigen detection on and within cells, with high resolution and specificity.