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Updated: Sep 27, 2026

Sample Preparation for Computed Tomography-based Three-dimensional Visualization of Murine Hind-limb Vessels
Published on: October 7, 2021
Background suppression using magnetization preparation for contrast-enhanced 3D MR angiography of the pelvic and
J T Winterer1, R Strecker, C Lohrmann
1Department of Diagnostic Radiology, University of Freiburg, Germany. jan.winterer@klinikum.uni-freiburg.de
Purpose:
To develop and evaluate non-slab-selective magnetization preparation in contrast-enhanced 3D-MR angiography.
Methods:
An ultrafast spoiled mr angiography sequence (FLASH) with non-selective inversion prepulses for background suppression was implemented on a 1.5 T MR system. In 11 patients gadobenate dimeglumine-enhanced mr-angiography of the pelvic and lower leg arteries was performed using the AngioSURF device. Source data was evaluated for contrast-to-noise-ratio, image quality and the extent of background suppression.
Results:
Background suppression and selective vessel contrast was excellent in all vascular levels. The mr protocol was comfortable and easy-to-handle. Abandonment of precontrast-series acquisition simplified the examination procedure markedly.
Conclusions:
Magnetization preparation provides efficient suppression of the background signal in contrast-enhanced 3D mr angiography of the pelvic and lower leg arteries. Since no subtraction technique is needed, moving-bed and whole body MRA-protocols can be simplified significantly.
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