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[Detection of TTV DNA and TTV IgG in 328 serum samples]
Objective:
To investigate the prevalence of TT virus(TTV) in a variety of populations in China.
Methods:
TTV DNA and anti TTV IgG were simultaneously tested by PCR and ELISA.
Results:
The positive rate of TTV DNA in the samples of 81 normal subjects, 92 blood donors, 123 hepatitis A-G patients and 32 hepatitis non A-G patients were 2.5%, 2.2%, 19.5% and 28.1%, respectively; and anti-TTV IgG was 1.2%, 3.7%, 26.8% and 34.4%, respectively. There were significant differences between the normal and the blood donor group and the hepatitis group; and among multi-infectious cases, the infection rate of TTV with HBV was as high as 75.0%.
Conclusion:
The investigation indicated that TTV infection was very popular in different groups. Some of the normal and blood donor groups infected with TTV could become healthy carries of virus. And the hepatitis patients were the high risk group. In addition, TTV may be transmitted via other pathways besides blood.