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Evaluation of the impact of a pharmaceutical care program in children with asthma
G González-Martin1, I Joo, I Sánchez
1Facultad de Química, Departamento de Farmacia, Pontificia Universidad Católica de Chile, Vicuña Mackenna 4860, Santiago, Chile. ggonzale@puc.cl
Insights
A pharmaceutical care program significantly improved quality of life for children with asthma, enhancing their daily activities, emotions, and symptom management. This asthma education and monitoring program showed positive impacts without altering spirometry results.
Area of Science:
- Pediatric Pulmonology
- Clinical Pharmacy
- Health Outcomes Research
Background:
- Asthma is a prevalent chronic respiratory condition in children, impacting their quality of life.
- Effective management of pediatric asthma requires comprehensive patient education and monitoring.
- Existing asthma care may not fully address the multifaceted needs of young patients.
Purpose of the Study:
- To evaluate the impact of a structured pharmaceutical care program on the quality of life in children with moderate asthma.
- To assess improvements in asthma knowledge, self-management, and symptom control through pharmacist intervention.
- To compare outcomes between children receiving pharmaceutical care and those receiving standard treatment.
Main Methods:
- A randomized controlled trial was conducted in a pediatric outpatient clinic.
- The intervention group received comprehensive asthma education, pharmacotherapy assessment, and monitoring.
- The control group received standard asthma care. Quality of life was measured using the Paediatric Asthma Quality of Life Questionnaire (PAQLQ) at baseline, 2, and 9 weeks. Spirometry was performed at the beginning and end of the study.
Main Results:
- Children in the pharmaceutical care group showed significant improvements in the activities, emotions, and symptoms domains of the PAQLQ compared to the control group.
- No significant changes in quality of life scores were observed in the control group.
- No significant differences in spirometric values were found between the groups post-intervention.
Conclusions:
- A dedicated pharmaceutical care program can substantially enhance the quality of life for pediatric asthma patients.
- Pharmacist-led asthma education and monitoring are effective strategies for improving patient-reported outcomes.
- While spirometry did not change, the program positively impacted children's daily functioning and emotional well-being related to asthma.
Abstract:
The objective of this study was to evaluate the impact of a pharmaceutical care program on children with asthma. A comprehensive asthma education and monitoring program that includes basic asthma knowledge, symptoms and exacerbation evaluation, pharmacotherapy assessment including inhaler technique, and quality of life measurements was developed and applied in an outpatient paediatric clinic of the Catholic University of Chile. All patients with moderate asthma scheduled for outpatient visits with their internist over a 1-year period were referred for pharmacist intervention. Patients (aged 7-17) with moderate asthma attending the clinic were allocated to the intervention (group A) or control group (group B). Intervention patients were educated on their disease, pharmacotherapy, self-management, and inhalation techniques. The group B were children with their regular treatment for asthma but without pharmaceutical intervention. A paediatric asthma quality of life questionnaire (PAQLQ) was applied to both groups at 0, 2, and 9 weeks to assess the quality of life. Spirometry was done at the beginning and at the completion of the 9-week study. Beta-agonists used by each patient were also recorded. Eleven children (10.0+/-0.7 years) were included in the pharmaceutical care program, and ten children (9.9+/-0.6 years) in group B. For the individual domains of activities (A), emotions (E), and symptoms (S) there was a significant improvement in the children who received pharmaceutical care in comparison with those who did not receive it. The scores of group B did not change during the 9 weeks of follow-up. There were no significant changes in spirometric values in either group.
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