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Updated: Aug 7, 2026

Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications
Published on: February 23, 2017
The fluorapatite-anorthite system in biomedicine
S Agathopoulos1, D U Tulyaganov, P A A P Marques
1Department of Ceramics and Glass Engineering, University of Aveiro, 3810-193, Aveiro, Portugal. akis@cv.ua.pt
Abstract:
Glasses and glass ceramics of fluorapatite-anorthite (eutectic composition) were produced and characterized in order to evaluate their potential application in biomedicine. Bio-reactivity was determined by in vitro tests by immersion of powders in simulated plasma liquids as well as by in vivo experiments by implantation in rabbits. According to the results, the investigated materials are bio-acceptable since no toxic or other harmful evidence was detected. Glass-ceramics showed remarkable inertness, whereas glasses spontaneously dissolved in SBF and after 1 week moderate formation of apatite was observed, that however ceased within a month.
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