Related Experiment Video
Updated: Sep 27, 2026

Novel In Vivo Micro-Computed Tomography Imaging Techniques for Assessing the Progression of Non-Alcoholic Fatty Liver Disease
Published on: March 24, 2023
[Comparison of contrast resolution between dynamic MRI and dynamic CT in liver scanning]
Akio Ogura1, Akira Miyai, Fumie Maeda
1Department of Radiology, Kyoto City Hospital.
Abstract:
Dynamic studies employing contrast agents have been used in the detection of hepatocellular carcinoma (HCC). Some studies have indicated that the detectability of small nodules in liver is significantly better with MRI dynamic study than with CT dynamic study. However, the reasons for this are unclear. In an attempt to clarify this difference, we compared contrast resolution using two contrast phantoms made for MRI and CT. Both phantoms were constructed using the same ratios of dilution of the contrast materials Gd-DTPA and iodine. The signal intensity of different dilution ratios of contrast medium were measured in order to compare the signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and contrast. The results showed that the contrast of phantoms in MRI and CT dynamic studies was almost the same except for certain MRI scan techniques. In terms of SNR and CNR, MRI dynamic study was superior to CT dynamic study. In addition, T(1) relaxation of the contrast agent should be considered for suitable scanning, because the contrast of MRI was affected by scan parameters.
Related Concept Videos
Imaging Studies I: CT and MRI
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
Magnetic Resonance Imaging
Imaging Studies for Cardiovascular System V: CT
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System IV: CMRI
