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Related Experiment Videos

Amniotic membrane transplantation for ocular surface reconstruction.

I Petric1, R Iveković, E Tedeschi-Reiner

  • 1Department of Ophthalmology, University Hospital Sestre Milosrdnice, Zagreb, Croatia.

Collegium Antropologicum
|January 17, 2003
PubMed
Summary

Human amniotic membrane transplantation effectively treats severe ocular surface diseases like bullous keratopathy and recurrent pterygia. It offers a viable alternative to penetrating keratoplasty when donor grafts are scarce.

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Area of Science:

  • Ophthalmology
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Severe ocular surface diseases, including bullous keratopathy and recurrent pterygia, pose significant clinical challenges.
  • Limited availability of donor grafts for penetrating keratoplasty necessitates alternative treatment strategies.

Purpose of the Study:

  • To evaluate the clinical outcomes of human amniotic membrane transplantation (AMT) in patients undergoing pterygium excision.
  • To assess the efficacy of AMT in managing bullous keratopathy.

Main Methods:

  • A consecutive series of 21 eyes underwent AMT between January 1999 and January 2001.
  • The study included 11 eyes with bullous keratopathy and 10 eyes with recurrent pterygia.

Main Results:

Related Experiment Videos

  • In bullous keratopathy cases, 72.7% achieved epithelization within 19.6 days, with satisfactory pain reduction.
  • The recurrence rate for recurrent pterygia treated with AMT was 20%.

Conclusions:

  • Human amniotic membrane transplantation is an effective treatment for severe ocular surface diseases.
  • AMT serves as a valuable alternative to penetrating keratoplasty, particularly in situations with graft scarcity.