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Updated: Aug 17, 2026
A Simple Bioassay for the Evaluation of Vascular Endothelial Growth Factors
Published on: March 15, 2016
[The prognostic value of vascular endothelial growth factor in breast cancer]
1Department of General Surgery, First Affiliated Hospital, WCUMS, Chengdu 610041, China.
Objective:
To define the relevance of VEGF status to the prognosis of breast cancer.
Methods:
The tissues of 70 invasive ductal breast carcinomas were evaluated for VEGF protein expression by immunohistochemistry LSAB method, and the prognostic value of VEGF status was assessed in combination with the follow-up data on those breast cancer patients.
Results:
VEGF status was inversely correlated with relapse-free survival and overall survival. Kaplan-Merier survival curve showed that VEGF-rich tumor group had higher relapse rate and mortality rate. Multivariate regression analysis confirmed that the VEGF status had certain prognostic value, but it could not be considered as an independent prognostic indicator.
Conclusion:
VEGF status is one of the significant prognostic indicators of breast cancer.
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