No hypothermic response to serotonin in 5-HT7 receptor knockout mice

P B Hedlund1, P E Danielson, E A Thomas

  • 1Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.

Summary

5-hydroxytryptamine (5-HT) causes hypothermia through the 5-HT(7) receptor. Oleamide induces hypothermia via a separate pathway, though it can also interact with the 5-HT(7) receptor.