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Lung transplantation and end of life issues in cystic fibrosis

P Aurora1, I M Lynn

  • 1Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK. paulaurora@yahoo.co.uk

Paediatric Respiratory Reviews
|January 18, 2003
PubMed

Insights

Lung transplantation for cystic fibrosis lung disease has poor outcomes and limited organ supply. Some children choose medical management and terminal care over this option.

Area of Science:

  • Pulmonology
  • Transplant Surgery
  • Pediatric Care

Background:

  • Lung transplantation is a treatment option for end-stage cystic fibrosis lung disease.
  • Outcomes remain suboptimal, and donor organ availability is restricted.
  • This influences treatment decisions for pediatric patients.

Purpose of the Study:

  • To review the current landscape of lung transplantation for cystic fibrosis.
  • To outline current referral guidelines and contraindications for lung transplantation.
  • To discuss contemporary practices in terminal care for these patients.

Main Methods:

  • Literature review of lung transplantation in cystic fibrosis.
  • Analysis of current referral criteria and contraindications.
  • Examination of terminal care protocols.

Main Results:

  • Lung transplantation for cystic fibrosis has historically yielded poor results.
  • Limited organ availability is a significant barrier to transplantation.
  • Alternative management, including terminal care, is a consideration for some patients.

Conclusions:

  • Lung transplantation for cystic fibrosis remains challenging due to outcomes and organ scarcity.
  • Careful consideration of referral guidelines and contraindications is essential.
  • Terminal care represents a valid alternative pathway for select pediatric patients.

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