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Related Concept Videos

Blood Transfusion and Agglutination02:45

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
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The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
Blood Transfusion01:15

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Related Experiment Video

Updated: Jul 24, 2026

Generation and Culture of Blood Outgrowth Endothelial Cells from Human Peripheral Blood
11:00

Generation and Culture of Blood Outgrowth Endothelial Cells from Human Peripheral Blood

Published on: December 23, 2015

Transfusion medicine: looking to the future.

Lawrence T Goodnough1, Aryeh Shander, Mark E Brecher

  • 1Department of Medicine, Washington University School of Medicine, St Louis, MO 63110, USA. goodnough@labmed.wustl.edu

Lancet (London, England)
|January 18, 2003
PubMed
Summary

Transfusion medicine faces future challenges in blood safety and supply, including pathogen inactivation and donor screening. Innovative strategies are crucial for global blood availability and patient safety.

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Last Updated: Jul 24, 2026

Generation and Culture of Blood Outgrowth Endothelial Cells from Human Peripheral Blood
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Area of Science:

  • Transfusion Medicine
  • Hematology
  • Public Health

Background:

  • Transfusion medicine has evolved into a patient-centered discipline facing significant future challenges.
  • Emerging issues like pathogen inactivation and enhanced donor screening impact blood supply affordability.
  • Alternatives for anemia management, such as oxygen carriers, require careful implementation.

Purpose of the Study:

  • To outline the key challenges and future directions in transfusion medicine.
  • To emphasize the critical need for blood safety and availability.
  • To highlight disparities in blood access for developing countries.

Main Methods:

  • Review of current trends and emerging issues in transfusion medicine.
  • Analysis of risks associated with transfusion, including viral transmission and bacterial contamination.
  • Discussion of potential solutions and strategies for future blood supply management.

Main Results:

  • Current viral transmission rates (HIV, HCV) are very low (approx. 1 in 2,000,000).
  • Bacterial contamination of platelets (1 in 2,000) and transfusion errors (1 in 800,000 mortality) remain critical concerns.
  • Significant disparities exist in blood safety and availability, particularly in developing nations.

Conclusions:

  • Addressing challenges in pathogen inactivation, donor screening, and new therapies is vital for transfusion medicine.
  • Minimizing transfusion risks and ensuring equitable access to safe blood are paramount.
  • Innovative strategies and resource commitment are essential to overcome global blood safety and availability difficulties.