Related Experiment Video
Updated: Jul 19, 2026

Methods for the Determination of Rates of Glucose and Fatty Acid Oxidation in the Isolated Working Rat Heart
Published on: September 28, 2016
Glucose-insulin-potassium, free fatty acids and acute myocardial infarction in man
Abstract:
In patients with stable coronary artery disease, a GIK solution may increase arterial glucose and the arterial-coronary sinus difference of glucose across the myocardium. In the same patients, GIK may reduce arterial free fatty acids as well as the arterial-coronary sinus difference of free fatty acids across the myocardium. As the arterial values of free fatty acids fall, so does the arterial-coronary sinus difference of free fatty acid across the myocardium, defining a myocardial threshold for free fatty acids of approximately 200 mEq/L. Glucose-insulin-potassium may lower free fatty acid values to near or below myocardial threshold in patients with acute myocardial infarction despite recurrent pain. Preliminary data suggest that GIK in the concentration and infusion rates used in this study may favorably influence survival in patients with acute myocardial infarction.
More Related Videos
Related Concept Videos
Insulin Secretory Vesicles
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Angina I: Introduction
Hypoglycemia
Hyperglycemia
Diabetic Neuropathy

