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Updated: Aug 10, 2026
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Demonstration of the Rat Ischemic Skin Wound Model
Published on: April 1, 2015
[Fos expression in rat skin after different incised wound healing interval]
1Institution of Forensic Sciences of Ministry of Justice, Shanghai 200063. liuningguo@163.net
Fa Yi Xue Za Zhi
|January 22, 2003
Abstract
Objective:
To investigate the expression of c-fos in rats' skin during wound healing.
Methods:
Immunohistochemistry was conducted on paraffin section from incised wounding model of rat skin.
Results:
Fos protein improved from the time of 10 min after wounding in the wound edge, then it reached peak at 3 h. 24 h after injury, the quantity of Fos expression had no difference with that of normal skin.
Conclusion:
Fos is sensitive after wound, but should be used with other criteria in wounding interval estimation as it's unstediness.
