Related Experiment Video
Updated: Sep 11, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
[Epidemiology of osteomyelitis and arthritis in infants]
Olfa Kaabachi1, Nabil Nessib, Lamia Thabet
1Service d'Orthopédie de l'Hôpital d'Enfants de Tunis, 1007 Tunis, Tunisle.
Insights
This study analyzed 206 infant cases of osteomyelitis and arthritis, finding Staphylococcus aureus most common in bone infections. Bacterial pathogens like Streptococcus pneumonia were frequently identified in joint infections.
Area of Science:
- Pediatric Orthopedics
- Infectious Diseases
- Microbiology
Background:
- Osteomyelitis and arthritis are significant pediatric bone and joint infections.
- Infants (3 months–3 years) present unique diagnostic and management challenges.
- Understanding causative pathogens is crucial for effective treatment.
Purpose of the Study:
- To retrospectively analyze pediatric osteomyelitis and arthritis cases.
- To identify common pathogens and infection sites in infants.
- To inform clinical practice and improve patient outcomes.
Main Methods:
- Retrospective study design over 10 years.
- Data collection from the pediatric orthopaedic unit of Tunis Children's Hospital.
- Analysis of 206 infant cases (3 months–3 years old).
Main Results:
- Infection involved the joint in 74.6% of cases.
- Lower limbs were the most common site for single infection foci (92.6%).
- Staphylococcus aureus was the predominant pathogen (52%), particularly in osteomyelitis. Enterobacteria (16%), Streptococcus (17.7%), and Haemophilus influenzae (5.3%) were common in arthritis.
Conclusions:
- Staphylococcus aureus is a primary cause of osteomyelitis in infants.
- Diverse bacterial pathogens contribute to pediatric arthritis.
- Prompt diagnosis and targeted antimicrobial therapy are essential.
Abstract:
A retrospective study realised over 10 years in the orthopaedic unit of the children's hospital of Tunis allowed to collect 206 cases of osteomyelitis and arthritis in infant (3 months--3 years old). In 74.6% of the cases, infection involved the joint. There is a single focus of the infection in 92.6% of the cases, more often at the lower limbs. The pathogen has been isolated in 33% of the cases. Staphylococcus aureus (52 %) is the more frequent pathogen, especially in osteomyelitis. Enterobateria (16%), Streptococcus (17.7%) (Streptococcus pneumonia: 10.7%), and Hemophylus influenzea (5.3%) were often isolated in arthritis.
Related Concept Videos
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Development of the Oral Microbiota

