Related Experiment Video
Updated: Sep 27, 2026

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
Published on: May 10, 2022
[New approaches to immune against hepatitis C virus]
1Department of Clinical Biochemistry, Sackler Faculty of Medicine, Tel-Aviv University, Israel.
Abstract:
Hepatitis C virus represents a global health problem as some 170 million individuals are infected worldwide. Studies on virus replication and pathogenesis are hampered by the lack of a reliable cell culture system. In addition, the high rate of mutations reflected in viral antigen variability complicates attempts to prepare an efficient vaccine against HCV. Recently some significant strides were made towards resolving some of the above-mentioned difficulties. The importance of several structural antigens i.e. HVR1 and CD81 was demonstrated with regard to the infection mechanism and as structures that may serve to immunize against the virus. A promising new approach of using recombinant DNA vaccines instead of protein vaccines is discussed.
Related Concept Videos
Hepatitis
Viral Hepatitis I: Introduction
Inhibitors of Viral Protein Synthesis
Antiviral Nucleoside Inhibitors
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
