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Progress in the control system of the undulation pump total artificial heart
Itsuro Saito1, Tsuneo Chinzei, Yusuke Abe
1Research Center for Advanced Science and Technology, The University of Tokyo, Japan. saito@bme.rcast.u-tokyo.ac.jp
Artificial Organs
|January 22, 2003
Summary
A new control method for the undulation pump total artificial heart (UPTAH) was developed. This advanced control system improved survival rates in goat models, maintaining the artificial heart
Area of Science:
- Biomedical Engineering
- Cardiovascular Devices
Background:
- The undulation pump total artificial heart (UPTAH) is a compact implantable device.
- Simultaneous generation of outflow and inflow by the UPTAH presents significant control challenges.
Purpose of the Study:
- To establish effective control methods specifically designed for the UPTAH.
- To evaluate the performance of a novel hierarchical control system for the UPTAH.
Main Methods:
- Development and implementation of a seven-category hierarchical control system.
- Integration of motor control, left-right flow balance, and physiological control strategies.
- In vivo testing of the UPTAH with the new control method in 48 goats.
Main Results:
- Six goats survived over one month, with one surviving for 63 days.
- The developed control scheme, including 1/R control, maintained the UPTAH in good condition in implanted animals.
- Demonstrated feasibility of maintaining UPTAH function in a large animal model.
Conclusions:
- The newly developed hierarchical control method is effective for UPTAH management.
- This control strategy shows promise for improving the viability of UPTAH as a cardiac support device.
- Further research is warranted to optimize UPTAH control for clinical application.