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Related Experiment Videos

Outflow control for avoiding atrial suction in a continuous flow total artificial heart.

Paul S Olegario1, Makoto Yoshizawa, Akira Tanaka

  • 1Graduate School of Engineering, Tohoku University, Sendai, Japan. paul@ecei.tohoku.ac.jp

Artificial Organs
|January 22, 2003
PubMed
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A new control algorithm prevents atrial wall suction in total artificial hearts (TAHs) by adjusting the right pump speed. This method ensures stable blood flow without reducing the left pump

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Devices
  • Artificial Organs

Background:

  • Continuous flow blood pumps (axial, centrifugal) are favored for total artificial hearts (TAHs) due to their compact design.
  • A key challenge with continuous flow pumps is their susceptibility to atrial wall suction, particularly during rapid increases in flow demand.
  • Atrial wall suction can compromise the function of TAHs and patient hemodynamics.

Purpose of the Study:

  • To develop and evaluate a novel control algorithm to prevent left atrial wall suction in TAHs.
  • To investigate a method that controls right pump speed to mitigate suction, rather than reducing left pump output.

Main Methods:

  • A control algorithm was designed to manage the rotational speed of the right centrifugal pump.

Related Experiment Videos

  • The algorithm was tested in a mock circulatory system and in acute animal experiments using adult goats with TAHs.
  • Two centrifugal pumps independently controlled cardiac output via a computer interface.

    • Main Results:

    • The developed control algorithm successfully prevented left atrial wall suction.
    • The method allowed for simultaneous physiological control of the artificial heart.
    • Experimental validation was achieved in both simulated and animal models.

    Conclusions:

    • Controlling the right pump speed is an effective strategy to prevent left atrial wall suction in TAHs.
    • This approach maintains cardiac output while ensuring stable atrial function.
    • The findings support the clinical applicability of this control strategy for TAH devices.