Myocardial damage in falciparum malaria detectable by cardiac troponin T is rare
A Günther1, M P Grobusch, H Slevogt
1Institut für Tropenmedizin, Charité, Humboldt-Universität zu Berlin, Germany.
Objectives:
To estimate the prevalence of myocardial damage in falciparum malaria by serum concentration of cardiac troponin T.
Methods:
Retrospective study of stored sera and patient files; assessment of acute myocardial damage by serum concentration or activity of cardiac troponin T, creatine kinase, creatine kinase MB and myoglobin and by routine electrocardiography.
Results:
A total of 161 patients with falciparum malaria were included in the study; troponin T was elevated in one case (0.6%), no CK-MB elevations were found, myoglobin was elevated in 10 of 161 patients (6.2%), all of whom were elderly and had concomitant elevated serum concentration levels of cystatin C; ECG abnormalities were seen in 23 patients.
Conclusion:
Assessed by troponin T, myocardial damage in falciparum malaria is rare.
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