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Related Experiment Videos

Endovascular stents for intermittent claudication.

P Bachoo1, P Thorpe

  • 1Ward 36, Aberdeen Royal Infirmary NHS Trust, Foresterhill, Aberdeen, Scotland, UK, AB25 2ZN. pb@doctors.org.uk

The Cochrane Database of Systematic Reviews
|January 22, 2003
PubMed
Summary

Endovascular stents combined with angioplasty do not improve walking distance for intermittent claudication. Current evidence is limited by small studies, necessitating larger trials for definitive conclusions on stent effectiveness.

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Area of Science:

  • Vascular Surgery
  • Interventional Cardiology

Background:

  • Endovascular stents are explored to enhance arterial patency post-angioplasty for intermittent claudication.
  • Percutaneous transluminal angioplasty (PTA) is a common treatment for peripheral artery disease.

Purpose of the Study:

  • To evaluate if endovascular stents improve lifestyle-limiting claudication symptoms compared to angioplasty alone.
  • To test the hypothesis that stenting does not offer additional benefit over PTA for claudication.

Main Methods:

  • Systematic review of randomized trials comparing angioplasty with stenting versus angioplasty alone.
  • Searched multiple databases (Cochrane, MEDLINE, EMBASE) and hand-searched journals up to 2002.
  • Assessed trial quality and extracted data on restenosis rates and walking distance.

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Main Results:

  • Included two trials with 104 patients, all with femoro-popliteal disease.
  • Palmaz stent use with angioplasty showed no significant advantage in arterial patency or walking distance compared to angioplasty alone.
  • No differences observed in secondary outcomes between the groups.

Conclusions:

  • Limited evidence from small, methodologically weak trials restricts conclusions on stent efficacy.
  • Larger, multicenter trials are required to definitively assess the role of endovascular stents in intermittent claudication.
  • Current data do not support routine stenting for improving claudication symptoms.