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Updated: Sep 27, 2026

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
Published on: August 14, 2015
CAMP and Ca2+ interplay: a matter of oscillation patterns
Manuela Zaccolo1, Tullio Pozzan
1Dulbecco Telethon Institute, Venetian Institute of Molecular Medicine, Via Orus 2, Padua, Italy. manuela.zaccolo@unipd.it
Abstract:
Ca(2+) and cAMP signalling pathways are tightly interconnected and the cellular effects mediated by the two second messengers depend strictly on reciprocal modulation. The signalling network that derives from such interplay holds the potential for expanding the information content of the signal enormously and, thus, can contribute substantially to the specificity and diversity of the response. Recent work points to interdependent Ca(2+) and cAMP oscillation patterns as a new paradigm for signal transduction.
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