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The Xenopus arx gene is expressed in the developing rostral forebrain
Heithem M El-Hodiri1, Xiu-Lan Qi, Daniel W Seufert
1Center for Molecular and Human Genetics, Children's Research Institute, 700 Children's Drive, Columbus, OH 43026, USA. ELH@pediatrics.ohio-state.edu
Development Genes and Evolution
|January 22, 2003
Abstract:
The human aristaless-related homeobox ( ARX) gene is mutated in several patients with X-linked mental retardation and/or other neurologic pathologies. We report the isolation and expression pattern of a Xenopus arx gene. Similar to other vertebrate arx genes, Xenopus arx is expressed in the developing telencephalon, diencephalon, and floor plate.