Related Experiment Videos
[Analysis of early feeding and gastrointestinal dysfunction in neonates with asphyxia]
1Department of Pediatrics, Second Xiangya Hospital, Central South University, Changsha 410011, China.
Insights
Early enteral feeding in neonates with perinatal asphyxia can cause gastrointestinal issues. Delaying feeding, especially on the first day, reduces the risk of complications like vomiting and distension.
Area of Science:
- Neonatal care
- Gastroenterology
- Perinatal medicine
Context:
- Perinatal asphyxia poses significant risks to newborns.
- Gastrointestinal (GI) complications are common in affected neonates.
- Enteral feeding is crucial for neonatal nutrition but can be challenging.
Purpose:
- To evaluate the impact of early enteral feeding on GI function in neonates with perinatal asphyxia.
- To determine the optimal timing for initiating enteral nutrition in this vulnerable population.
Summary:
- Analysis of 84 neonates with perinatal asphyxia revealed high rates of GI dysfunction (vomiting, abdominal distension, gastric bleeding) within the first four days of life.
- GI dysfunction decreased significantly with each subsequent day after birth.
- Fasting on the first day resulted in a lower incidence of GI dysfunction compared to early feeding with dextrose or dilute milk.
Impact:
- Findings suggest that early enteral feeding, particularly within the first three days, is not optimal for neonates experiencing perinatal asphyxia.
- A strategy of withholding enteral feeds on the first day is recommended to minimize GI complications.
- This research informs clinical practice guidelines for managing nutrition in neonates with perinatal asphyxia.
Objective:
This article was to investigate the effect of early initiation of enteral feeding in neonates with perinatal asphyxia on gastrointestinal function.
Methods:
Eighty-four cases of enteral feeding of neonates with asphyxia were analysed.
Results:
The common dysfunctions were vomiting and abdominal distension, gastric bleeding as well; the percentages of gastrointestinal dysfunction in the early four days were 65.2%, 24.1%, 8.9%, 1.12% respectively and presented a decreasing tendency following the increasing days after birth; The percentage of gastrointestinal dysfunction on the first day was the highest in the early three days (P < 0.05) and not only dextrose but also dilute milk resulted in the dysfunctions. Fasting caused the lower percentage of the dysfunction(2.15%, P < 0.05), but dextrose and dilute milk had no significant difference(P > 0.05).
Conclusion:
It's not optimal for neonates with asphyxia to initial early enteral feeding, especially in the early three days; it's optimal for the neonates with asphyxia not to be fed on the first day.