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Related Experiment Videos

Sri Lankan Twin Registry.

Athula Sumathipala1, Sisira Siribaddana, Nimali De Silva

  • 1Section of Epidemiology, Institute of Psychiatry, Kings College, University of London, Essex, UK. spjuats@iop.kcl.ac.uk

Twin Research : the Official Journal of the International Society for Twin Studies
|January 23, 2003
PubMed
Summary

Sri Lanka

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Area of Science:

  • Human genetics
  • Bioethics
  • Population studies

Background:

  • Sri Lanka possesses significant genetic diversity across its five major population groups.
  • The establishment of the first twin registry in a developing nation.
  • Addressing the nascent field of bioethics in Sri Lanka through tailored guidelines.

Purpose of the Study:

  • To establish a comprehensive twin registry in Sri Lanka.
  • To develop and validate a zygosity determination questionnaire.
  • To create ethical frameworks for twin research from a developing-world perspective.

Main Methods:

  • Recruitment of 4600 twin pairs via media campaigns and established cohorts (volunteer, birth registration, community-based).
  • Utilizing nationwide birth records (1992-1997) for a younger twin cohort.

Related Experiment Videos

  • Adaptation and validation of a zygosity determination questionnaire.

    • Main Results:

    • Successfully established multiple twin cohorts, including a nationwide younger cohort.
    • Validated a practical zygosity determination questionnaire for diverse populations.
    • Developed unique ethical guidelines for twin research relevant to developing countries.

    Conclusions:

    • The Sri Lankan twin registry is a pioneering initiative in the developing world.
    • The registry provides a valuable resource for genetic diversity and twin studies.
    • Future plans include capacity building, multidisciplinary research, and service development for twins.