Related Experiment Video
Updated: Sep 27, 2026

Microscopic Replantation of Penile Glans Amputation Due to Circumcision
Published on: June 3, 2022
EMLA cream versus dorsal penile nerve block for postcircumcision analgesia in children
W Y Choi1, M G Irwin, T W C Hui
1Department of Anaesthesia and Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong. reginachoi@hotmail.com
Insights
EMLA cream provides effective post-circumcision pain relief with minimal side effects. While it didn't reduce pain scores, it offered a simple method for analgesia.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Pain Management
Background:
- Post-circumcision pain management is crucial for infant well-being.
- Effective and safe analgesia methods are continuously sought.
Purpose of the Study:
- To compare the efficacy of EMLA cream with a dorsal penile nerve block for post-circumcision analgesia.
- To evaluate pain scores and duration of analgesia.
Main Methods:
- Prospective, randomized, double-blinded trial.
- EMLA cream and sodium chloride solution dorsal penile block vs. placebo cream and bupivacaine dorsal penile nerve block.
- Pain assessment using modified Children's Hospital of Eastern Ontario Pain Scale; duration of block assessed by time to first postoperative analgesic.
Main Results:
- No significant difference in pain scores between groups.
- Bupivacaine dorsal penile nerve block provided significantly longer analgesia (P = 0.003).
- Low incidence of adverse effects, including minimal vomiting, in both groups.
Conclusions:
- Preoperative EMLA cream application is an effective and simple method for post-circumcision analgesia.
- EMLA cream is associated with a very low incidence of adverse effects.
- Dorsal penile nerve block with bupivacaine offers prolonged analgesia but EMLA cream provides a simpler alternative.
Abstract:
We conducted a prospective, randomized, double-blinded trial comparing preoperative application of EMLA cream and sodium chloride solution dorsal penile block (n = 31) with placebo cream and bupivacaine dorsal penile nerve block (n = 32) for postcircumcision analgesia. Pain was assessed using modified Children's Hospital of Eastern Ontario Pain Scale and the duration of block by the time to requirement of first dose of postoperative analgesic. There was no difference in Children's Hospital of Eastern Ontario Pain Scale between the two groups, but bupivacaine dorsal penile nerve block resulted in longer analgesia (P = 0.003). There were no local or systemic complications related to either technique, and there was a very small incidence of vomiting. We conclude that preoperative application of EMLA cream is an effective and simple method to produce postcircumcision analgesia with a very small incidence of adverse effects.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
