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Chimera: construction of chimeric sequences for phylogenetic analysis.
1Dalicon BV, Toernooiveld 218, 6525 EC Nijmegen (NL). jackl@dalicon.com
Bioinformatics (Oxford, England)
|January 23, 2003
Summary
Chimera software enables the creation of chimeric protein and nucleic acid sequences by combining data from multiple files. This tool facilitates interactive selection of genes and species for sequence concatenation, outputting results in PHYLIP or NEXUS formats.
Area of Science:
- Bioinformatics
- Computational Biology
- Molecular Biology
Background:
- The Chimera computer program is available for download, including supporting and example files.
- Access the software and associated files at http://www.dalicon.com/chimera/.
Purpose of the Study:
- To introduce Chimera, a software tool for constructing chimeric protein or nucleic acid sequences.
- To provide a user-friendly method for combining genetic data from multiple sources.
Main Methods:
- The Chimera program concatenates sequences from two or more input files in PHYLIP format.
- Users can interactively select specific genes and species from the input data.
- The resulting chimeric sequence is saved into a single output file.
Main Results:
- Successfully creates chimeric protein or nucleic acid sequence files.
- Supports interactive selection of genetic elements and species.
- Outputs concatenated sequences in standard PHYLIP or NEXUS formats.
Conclusions:
- Chimera offers a straightforward method for generating chimeric sequences.
- The software simplifies the process of combining genetic information for research.
- Facilitates the creation of complex sequence data for further analysis.