Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Angiogenesis in brain tumors.

M Beatriz S Lopes1

  • 1Department of Pathology-Neuropathology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908-0214, USA. msl2e@virginia.edu

Microscopy Research and Technique
|January 23, 2003
PubMed
Summary

Angiogenesis, the formation of new blood vessels, is crucial in brain conditions like tumors and ischemia. This review explores how angiogenic growth factors influence brain

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

N-O-D-26-00712-Molecular Classification of Pituitary Neuroendocrine Tumors (PitNETs): Implications for Clinical Management.

Neuro-oncology·2026
Same author

Intracranial solitary fibrous tumor with myxoid features: An unusual presentation.

Journal of neuropathology and experimental neurology·2026
Same author

Development, validation, and utility of a clinically applicable methylation classifier for recurrence risk prediction in meningiomas.

Acta neuropathologica communications·2025
Same author

Co-occurrence of Functional Gonadotroph Adenoma and Lactotroph Adenoma: A Case Report and Literature Review.

AACE clinical case reports·2023
Same author

Impact of histopathological classification of non-functioning adenomas on long term outcomes: comparison of the 2004 and 2017 WHO classifications.

Pituitary·2022
Same author

World Health Ozganization 2017 Classification of Pituitary Tumors.

Endocrinology and metabolism clinics of North America·2020

Area of Science:

  • Neuroscience
  • Cell Biology
  • Oncology

Background:

  • Angiogenesis is a vital process for forming new blood vessels from existing ones.
  • It involves coordinated steps like cell migration and proliferation, regulated by various factors.
  • This process is implicated in hypoxic/ischemic brain conditions and malignant tumors.

Purpose of the Study:

  • To review the role of angiogenic growth factors in brain conditions.
  • To examine their involvement in neoplastic and reactive brain processes.

Main Methods:

  • Literature review of recent data on angiogenic growth factors.
  • Analysis of their function in brain pathologies.

Main Results:

  • Angiogenesis is a key feature in central nervous system hypoxic/ischemic events.
  • Glioblastomas exhibit significant angiogenic activity, among the highest in human tumors.

Conclusions:

  • Angiogenic growth factors play a critical role in brain tumor development and other reactive conditions.
  • Understanding these factors is crucial for therapeutic strategies in brain pathologies.

Related Experiment Videos