Related Experiment Videos
[Expression of bone morphogenetic protein (BMP)-2, 4 in mouse embryonic tooth during the bud stage]
Abstract
Objective:
The purpose of this paper was to investigate the distributions of bone morphogenic protein (BMP)-2, 4 in the developing molars of mice during the bud stage and, the functional relationship between BMP-2 and BMP-4.
Methods:
The distribution of BMP-2, 4 were examined in developing mouse molars on the 14th (the 14th embryonic day), using monoclonal antibodies and immunohistochemistry methods.
Results:
BMP-2, 4 were detected both in the epithelial cells and dental mesenchyme cells.
Conclusion:
There is a similar distribution pattern between BMP-2 and BMP-4. Therefore, there may be a functional relationship between BMP-2 and BMP-4 during the development of mouse embryonic teeth in the bud stage.