Self-prescribed laxative use: a drug-utilization review.

Area of Science:

• Pharmacology
• Gastroenterology
• Public Health

Background:

• Laxatives are widely available over-the-counter (OTC) medications.
• Self-prescription of laxatives raises concerns regarding appropriate usage and potential adverse effects.

Purpose of the Study:

• To investigate the reasons behind self-prescribing laxatives.
• To understand the usage patterns and tolerance of OTC laxatives.
• To identify factors influencing laxative choice and identify potential risks associated with misuse.

Main Methods:

• A survey was conducted across 70 pharmacies in the Campania region of southern Italy.
• Questionnaires were distributed to purchasers of OTC laxatives between November 1999 and February 2000.
• Data collected included demographics, reasons for purchase, administration route, source of recommendation, usage correctness, and reported adverse effects.

Main Results:

• 7324 individuals completed the survey; the average age was 45.9 years, with 23.8% being elderly.
• Oral laxatives were preferred by 77.6%, while 22.4% opted for rectal administration.
• Physicians (37.7%) and pharmacists (20.5%) were key influencers, alongside relatives, acquaintances, and advertisements.
• Only 59.8% used laxatives correctly; 58.2% consulted a healthcare professional for constipation.
• Adverse effects, primarily gastrointestinal, were reported by 6.1% of respondents.

Conclusions:

• A significant proportion of individuals self-prescribing laxatives do so without proper guidance, leading to incorrect usage.
• The potential for long-term laxative abuse poses serious health risks, including masking underlying conditions.
• Healthcare professionals must actively counsel patients on the safe and effective use of OTC laxatives.