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The genomics of insecticide resistance
John G Oakeshott1, Irene Home, Tara D Sutherland
1Commonwealth Scientific and Industrial Research Organisation Entomology, Clunies Ross Street, Black Mountain, ACT 2601, Australia. John.Oakeshott@csiro.au
Genome Biology
|January 24, 2003
Abstract:
Genomic technologies are revealing several mechanisms of insecticide resistance involving enhanced detoxification or reduced target-site sensitivity that had previously defied molecular analyses. Genome projects are also revealing some potentially far-reaching consequences for pest-insect genomes of the rapid accumulation of multiple resistance mutations in very short periods of evolutionary time.