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Flavanone glycosides from Miconia trailii
Zhizhen Zhang1, Hala N ElSohly, Xing-Cong Li
1National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, and Department of Pharmacology, School of Pharmacy, University of Mississippi, University, Mississippi 38677, USA.
Journal of Natural Products
|January 25, 2003
Summary
Two new flavanone glycosides, miconioside A and miconioside B, were isolated from Miconia trailii. Their structures were determined using spectroscopic methods, including 2D NMR analysis.
Area of Science:
- Phytochemistry
- Natural Products Chemistry
- Organic Chemistry
Background:
- Miconia trailii is a plant species known for its potential medicinal properties.
- Phytochemical investigations aim to identify bioactive compounds from plant sources.
Purpose of the Study:
- To isolate and characterize new compounds from the ethanol extract of Miconia trailii twigs and leaves.
- To elucidate the chemical structures of isolated compounds using spectroscopic techniques.
Main Methods:
- Assay-guided fractionation of the ethanol extract.
- Structure elucidation using spectroscopic methods, including 2D Nuclear Magnetic Resonance (NMR).
Main Results:
- Two new flavanone glycosides, miconioside A and miconioside B, were identified.
- Six known compounds were also isolated: matteucinol 7-O-beta-d-apiofuranosyl(1-->6)-beta-d-glucopyranoside, matteucinol, bartogenic acid, arjunolic acid, myrianthic acid, and stigmast-4-ene-3,6-dione.
- The structures of all eight compounds were confirmed through detailed spectroscopic analysis.
Conclusions:
- The study successfully identified and characterized novel flavanone glycosides from Miconia trailii.
- The findings contribute to the understanding of the phytochemical profile of Miconia trailii and may inform future research on its biological activities.