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A new platelet parameter, the mean platelet component, can demonstrate abnormal platelet function and structure in
D R Brummitt1, H F Barker, N Pujol-Moix
1Department of Haematology, Rotherham General Hospitals NHS Trust, Rotherham, S60 2UD, UK.
Clinical and Laboratory Haematology
|January 25, 2003
Abstract:
The mean platelet component (MPC) is a new platelet parameter generated by the Bayer ADVIA 120 full blood count analyser as part of the routine complete blood count (CBC) test cycle. We report a case of myelodysplasia with bleeding complications and abnormal template bleeding time in whom low mean platelet component parameters were associated with partial platelet granule deficiency, demonstrated by transmission electron microscopy. We suggest that the mean platelet component is an inexpensive and rapid test to screen for platelet dysfunction related to ultrastructural abnormalities in myelodysplasia.