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Nonconjugative transposition of the vanB-containing Tn5382-like element in Enterococcus faecium
Kristin H Dahl1, Torunn P Røkenes, Eirik W Lundblad
1Department of Microbiology and Virology, University and University Hospital of Tromsø Norwegian Institute of Gene Ecology, Tromsø, Norway.
Antimicrobial Agents and Chemotherapy
|January 25, 2003
Abstract:
The vanB2 operon encoding glycopeptide resistance is an integral part of the putative conjugative transposon Tn5382. Characterization of clinical glycopeptide resistant derivatives from an epidemic ampicillin-resistant Enterococcus faecium strain showed precise chromosomal or plasmid insertions of a vanB2-containing Tn5382-like element. Conjugative transposition of the Tn5382-like element was not demonstrated in retransfer studies.