Diffusion magnetic resonance imaging in infantile neuroaxonal dystrophy
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Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
Published on: July 28, 2013
1Department of Radiology, Ege University Hospital, Bornova, Izmir, Turkey. rnsener@hotmail.com
Journal of Computer Assisted Tomography
|January 25, 2003
Abstract:
A 7-month-old girl with infantile neuroaxonal dystrophy is reported. In diffusion MRI, the pyramidal tracts and dentate nuclei had high signal on b = 1,000 s/mm2 images and low apparent diffusion coefficient (ADC) values. This pattern likely reflected the presence of abnormal (dystrophic) axons with restricted mobility of water molecules. A reverse pattern was evident in the cerebellar cortex with high ADC values. This was likely a reflection of dysmyelination or lack of myelination.

