Fever without apparent source on clinical examination

Related Experiment Videos

Paul L McCarthy1

  • 1Section of General Pediatrics, Yale University School of Medicine, New Haven, Connecticut 06510-8064, USA. paul.mccarthy@yale.edu

Insights

Pediatric infectious diseases, including fever without source and prolonged fever, require careful evaluation. This review covers recent literature on diagnosis and management for infants and children in office practices.

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Clinical Practice

Background:

  • Common pediatric infectious diseases present diagnostic challenges in office settings.
  • Fever without apparent source and prolonged fever of unknown origin are frequent concerns.

Purpose of the Study:

  • To review recent literature on the evaluation and management of acute fevers without source in children.
  • To discuss the approach to prolonged fevers of unknown origin in pediatric patients.
  • To cover lower respiratory infections in children.

Main Methods:

  • Literature review of recent publications.
  • Synthesis of current evidence on epidemiology, pathophysiology, diagnosis, and therapy.
  • Focus on specific age groups: infants <90 days, children 3-36 months, and children with prolonged fever.

Main Results:

  • Provides updated information on managing febrile illnesses where the source is not immediately apparent.
  • Offers guidance on evaluating children with fevers lasting over 7-10 days without a diagnosis.
  • Includes insights into lower respiratory infections.

Conclusions:

  • Emphasizes the importance of a systematic approach to febrile children in pediatric practice.
  • Highlights recent advancements in understanding and treating common pediatric infectious diseases.
  • Aids clinicians in diagnosing and managing complex fever presentations.

Related Concept Videos

Types of Fever01:25

Types of Fever

Fever can be triggered by several factors, including infections, nervous system disorders, certain cancers, blood diseases like leukemia, embolism, thrombosis, heatstroke, dehydration, surgical trauma, crushing injuries, and allergic reactions.
Here are the different types of fever:
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Patterns of Fever01:26

Patterns of Fever

Before understanding the types and patterns of fever, it is essential to know its phases.
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Acute Pharyngitis01:30

Acute Pharyngitis

Introduction
Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
Classification
Acute pharyngitis can be categorized based on its underlying cause: