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Obstructive uropathy induced bladder dysfunction can be reversible: bladder compliance measures before and after
Wendy W Leng1, Edward J McGuire
1Department of Urology, University of California San Francisco, San Francisco, California, USA.
The Journal of Urology
|January 25, 2003
Summary
Relieving bladder outlet obstruction significantly improves bladder compliance in men with obstructive uropathy. This intervention offers a potential solution for improving bladder function in elderly patients with lower urinary tract symptoms.
Area of Science:
- Urology
- Nephrology
- Geriatrics
Background:
- Abnormal bladder compliance is a common issue in obstructive uropathy.
- Lower urinary tract symptoms (LUTS) in elderly men can be linked to bladder outlet obstruction (BOO).
- Understanding the impact of BOO relief on bladder compliance is crucial for patient management.
Purpose of the Study:
- To investigate the effect of relieving bladder outlet obstruction on bladder compliance.
- To assess if treatment of BOO can improve bladder function in men with LUTS.
Main Methods:
- Prospective study of 9 men with non-neurogenic LUTS and proven BOO.
- Videourodynamics used to measure bladder compliance (ml/cm H2O) before and 1 month after treatment.
- Treatment included transurethral prostate procedures or urethral balloon dilation.
Main Results:
- Pre-treatment mean bladder compliance was 3.06 ml/cm H2O.
- Post-treatment mean bladder compliance significantly increased to 13.53 ml/cm H2O (p=0.0117).
- Videourodynamics confirmed successful relief of obstruction in all patients.
Conclusions:
- Relief of bladder outlet obstruction can significantly improve bladder compliance.
- This improvement is achievable even in elderly patients with long-standing LUTS.
- The findings suggest a potential therapeutic benefit of BOO relief for bladder function.