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[Toxicity of microcystin and its bioaccumulation effect]
Haixia Sui1, Weixing Yan, Haibin Xu
1Institute of Food Safety Control and Inspection, Ministry of Health, Beijing 100021, China.
Wei Sheng Yan Jiu = Journal of Hygiene Research
|January 28, 2003
Abstract:
Microcystins are cyclic heptapeptide hepatotoxins from certain cyanobacteria. It can inhibit hepatic protein phosphatase 1 and 2A activities, break the balance between protein phosphorylation and phosphorylysis, causing liver damage even necrocytosis. Furthermore, it is a strong tumor promoter. Yet, its hazard received little study. This paper presents a latest review of toxicity and bioaccumulation of Microcystins.