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Digital algorithm for dispersion correction in optical coherence tomography for homogeneous and stratified media
Daniel L Marks1, Amy L Oldenburg, J Joshua Reynolds
1Department of Electrical and Computer Engineering, Beckman Institute of Advanced Science and Technology, University of Illinois at Urbana-Champaign, Urbana, IL 61801, USA.
Applied Optics
|January 28, 2003
Summary
We developed a numerical algorithm to correct blurring in optical coherence tomography (OCT) images caused by material dispersion. This method improves image quality for various materials, enhancing OCT
Area of Science:
- Biomedical Optics
- Image Processing
- Materials Science
Background:
- Optical Coherence Tomography (OCT) resolution is limited by blurring from material dispersion.
- Accurate OCT imaging requires addressing dispersion effects in various media.
Purpose of the Study:
- To present a numerical algorithm for correcting material dispersion in OCT reflectance data.
- To demonstrate the algorithm's effectiveness in homogeneous and stratified media.
Main Methods:
- Development of a computational algorithm for dispersion correction.
- Implementation using the fast Fourier transform (FFT).
- Experimental validation using polydimethylsiloxane microfluidic structures and glass slides.
Main Results:
- Successful correction of material dispersion-induced blurring in OCT images.
- Demonstrated applicability to both homogeneous and stratified media.
- Algorithm's efficiency shown through experimental imaging of microfluidic devices and glass slides.
Conclusions:
- The proposed algorithm effectively corrects material dispersion in OCT.
- Dispersion correction is crucial for OCT imaging of thick or highly dispersive samples.
- The FFT-based method offers an efficient solution for enhancing OCT image resolution.