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Updated: Aug 8, 2026

Investigating the Neural Mechanisms of Aware and Unaware Fear Memory with fMRI
Published on: October 6, 2011
Prefrontal cortex: procedural sequence learning and awareness
E M Robertson1, A Pascual-Leone
1Laboratory for Magnetic Brain Stimulation, Behavioral Neurology Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, KS 454, 02215, Boston, MA, USA.
Abstract:
Activation of the prefrontal cortex has been linked to awareness during sequence-learning tasks. A recent study, however, finds activation of the prefrontal cortex during such tasks regardless of awareness. So what is the neurophysiological basis of awareness, and what is the role of the prefrontal cortex in sequence learning?
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