Genetic approach to chemical genetics

A multi-variant, viral dynamic model of genotype 1 HCV to assess the in vivo evolution of protease-inhibitor resistant variants.

PLoS computational biology·2010

Rapid decrease of wild-type hepatitis C virus on telaprevir treatment.

Antiviral therapy·2009

Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: structure of lck/imatinib complex.

Proteins·2007

CORES: an automated method for generating three-dimensional models of protein/ligand complexes.

Journal of medicinal chemistry·2004

A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.

Biochimica et biophysica acta·2002

Drug type contributions to pharmaceutical innovation: A USA-China comparative analysis.

Drug discovery today·2026

Can agentic AI dent Eroom's Law? Large reasoning models across the drug discovery and development pipeline.

Drug discovery today·2026

Tumor hypoxia: Molecular pathways and therapeutic interventions.

Drug discovery today·2026

Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities.

Drug discovery today·2026

Single-cell and spatial transcriptomic insights into fibrotic mechanisms and therapeutic opportunities.

Drug discovery today·2026

Deubiquitinase inhibitors: from evolving concepts to preclinical evaluation.

Drug discovery today·2026

Lateral flow immunoassays: challenges and innovations.

Clinica chimica acta; international journal of clinical chemistry·2026

Use of a Self-Irrigating Bipolar Sealer for Bilateral C2 Nerve Root Ligation During Atlantoaxial Instrumented Fusion.

Cureus·2026

Spectrofluorometric and spectrophotometric assay of anticancer drug ensartinib using ion-pair complex formation reaction with eosin Y.

Scientific reports·2026

A simple and sensitive QuEChERS-based LC-MS/MS method for quantifying 30 per- and polyfluoroalkyl substances (PFAS) in human serum: application to firefighter biomonitoring.

Talanta·2026

Development of a thin-layer chromatography-angiotensin-converting enzyme bioassay coupled with digital image analysis for effect-directed screening of enzyme inhibitors.

Journal of chromatography. A·2026

Highly sensitive simultaneous lateral flow assay for the detection of mycotoxins based on multichromatic metal-organic framework encapsulated fluorescent metal nanoclusters.

Food chemistry·2026

Related Experiment Videos

Genetic approach to chemical genetics

Related Concept Videos

A multi-variant, viral dynamic model of genotype 1 HCV to assess the in vivo evolution of protease-inhibitor resistant variants.

Rapid decrease of wild-type hepatitis C virus on telaprevir treatment.

Classifying protein kinase structures guides use of ligand-selectivity profiles to predict inactive conformations: structure of lck/imatinib complex.

CORES: an automated method for generating three-dimensional models of protein/ligand complexes.

A mutational analysis of the active site of human type II inosine 5'-monophosphate dehydrogenase.

Drug type contributions to pharmaceutical innovation: A USA-China comparative analysis.

Can agentic AI dent Eroom's Law? Large reasoning models across the drug discovery and development pipeline.

Tumor hypoxia: Molecular pathways and therapeutic interventions.

Degraders of histone lysine methyltransferases: Progress, challenges, and opportunities.

Single-cell and spatial transcriptomic insights into fibrotic mechanisms and therapeutic opportunities.

Deubiquitinase inhibitors: from evolving concepts to preclinical evaluation.

Lateral flow immunoassays: challenges and innovations.

Use of a Self-Irrigating Bipolar Sealer for Bilateral C2 Nerve Root Ligation During Atlantoaxial Instrumented Fusion.

Spectrofluorometric and spectrophotometric assay of anticancer drug ensartinib using ion-pair complex formation reaction with eosin Y.

A simple and sensitive QuEChERS-based LC-MS/MS method for quantifying 30 per- and polyfluoroalkyl substances (PFAS) in human serum: application to firefighter biomonitoring.

Development of a thin-layer chromatography-angiotensin-converting enzyme bioassay coupled with digital image analysis for effect-directed screening of enzyme inhibitors.

Highly sensitive simultaneous lateral flow assay for the detection of mycotoxins based on multichromatic metal-organic framework encapsulated fluorescent metal nanoclusters.

Related Experiment Videos

Genetic approach to chemical genetics

Related Concept Videos

Related Articles