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Challenges and opportunities in evaluating diagnostic tests
1University of North Carolina at Chapel Hill, CB #7080 724 Burnett-Womack, Chapel Hill, NC 27599-7080, USA. ransohof@med.unc.edu
Abstract:
The field of clinical research conducted to evaluate diagnostic tests has evolved substantially over the last 25 years. This article discusses three current challenges and opportunities in conducting such research: the limitations of the "traditional focus" of clinical epidemiology in evaluating tests; how different decision makers use data produced by clinical epidemiology research, and what those uses mean for future research; and special challenges and opportunities in evaluating molecular-based tests.
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