Related Experiment Video
Updated: Aug 10, 2026
Mouse Model for Pancreas Transplantation Using a Modified Cuff Technique
Published on: December 16, 2017
Successful surgical salvage of pancreas allograft
Elena Orsenigo1, Marco Cristallo, Carlo Socci
1Department of Surgery, San Raffaele Scientific Hospital, Milan, Italy. elenaors@libero.it.
Background:
Early and late complications related to the pancreas after simultaneous kidney-pancreas transplantation (SKPT) frequently result in graft loss. The authors describe a surgical rescue technique that allows salvage of the pancreatic graft when surgical complications appear after the transplant.
Methods:
Of 158 patients who underwent SKPT, 7 were identified with posttransplant complications that required surgical salvage of the pancreas allograft. The surgical salvage technique consisted of the following: pancreatoduodenectomy with conversion from whole-pancreas transplant with bladder or enteric diversion to segmental graft with duct injection (three cases) and conversion from whole-pancreas transplant with duct injection (four cases).
Results:
Five of seven pancreas allografts are still functioning, with a mean follow-up of 28 months (range, 6-42 months).
Conclusion:
The described surgical treatment may be useful for surgical salvage of the pancreatic allograft, without major impairment of endocrine function.
