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Updated: Jul 31, 2026

Automated Hydrophobic Interaction Chromatography Column Selection for Use in Protein Purification
Published on: September 21, 2011
[Development of column switching systems in industrial gas chromatography]
1National Chromatographic R. & A. Center, Laboratory of Chromatography, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, 116011.
Abstract:
According to the home-made requirement of column switching systems in 23 industrial gas chromatographs in 300,000 Tons of olefin plant, based on the research work of the expert system on gas chromatography and movement laws of compounds of interest in columns, the suitable stationary phases were defined, and the column switching systems were designed by using combined cutting techniques which consist of backflushing, fore-flushing and heart cutting, and by controlling column lengths, flows, flow directions and temperatures. The practical applications showed the column systems satisfy the on-line monitoring requirement of the production process and can be used continually for 1-3 years.
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