Refining the public health response to primary meningococcal conjunctivitis
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Published on: November 5, 2019
Roslyn G Poulos1, Elizabeth J Smedley, Mark J Ferson
1School of Public Health and Community Medicine, the University of New South Wales, Sydney, New South Wales.
Abstract:
Primary meningococcal conjunctivitis (PMC) is accepted as an uncommon condition. This report describes two recent cases of PMC in newborn infants in a hospital nursery. In both cases the organisms identified were non-groupable strains of N. meningiditis, considered to be of low pathogenic potential. Both infants received systemic therapy and recovered without sequelae. The Guidelines for the early clinical and public health management of meningococcal disease in Australia recommend the notification of PMC to public health authorities and chemoprophylaxis of contacts. However, our 2 cases suggest that the guidelines should allow for an assessment of risk in determining the public health response. This assessment should include the severity of the conjunctivitis and the serogroup of the N. meningitidis isolate.
Insights
Primary meningococcal conjunctivitis (PMC) is rare in newborns. These cases suggest current guidelines for managing PMC and its contacts may need risk assessment based on severity and bacterial strain.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Neonatal Care
Background:
- Primary meningococcal conjunctivitis (PMC) is considered uncommon.
- Neisseria meningitidis is a significant pathogen, typically causing meningitis and sepsis.
- Current Australian guidelines recommend notification and chemoprophylaxis for all PMC cases.
Observation:
- Two cases of PMC in newborn infants in a hospital nursery are reported.
- Both infants were infected with non-groupable strains of N. meningitidis, typically of low pathogenic potential.
- Both infants received systemic therapy and recovered fully without complications.
Findings:
- The identified N. meningitidis strains were non-groupable and of low pathogenic potential.
- The infants recovered without sequelae after systemic treatment.
- These cases challenge the universal application of current management guidelines.
Implications:
- Public health guidelines for PMC management may require revision.
- Risk assessment, including conjunctivitis severity and bacterial serogroup, should inform public health responses.
- This approach could optimize resource allocation and contact management for meningococcal disease.
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