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Nonlinear model for offline correction of pulmonary waveform generators
Jeffrey S Reynolds1, Kimberly J Stemple, Raymond A Petsko
1Engineering and Controls Technology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA. JReynolds@cdc.gov
IEEE Transactions on Bio-Medical Engineering
|January 29, 2003
Summary
Motor-driven piston pumps used for respiratory testing can distort flow-time profiles due to gas compression. A new nonlinear model and correction method significantly reduce errors in pulmonary function equipment testing.
Area of Science:
- Biomedical Engineering
- Respiratory Physiology
Background:
- Motor-driven piston pumps are standard for testing respiratory equipment like spirometers and peak expiratory flow (PEF) meters.
- Gas compression within these generators can distort the accuracy of flow-time profiles, impacting test results.
Purpose of the Study:
- To develop and validate a nonlinear model and compensation method for gas compression in pulmonary waveform generators.
- To improve the accuracy of respiratory function equipment testing by mitigating flow-time profile distortion.
Main Methods:
- A nonlinear model of the motor-driven piston pump generator was developed.
- A method to compensate for gas compression effects was implemented.
- The model and correction procedure were tested using 26 American Thoracic Society standard flow-time waveforms on Assess and Micro DiaryCard PEF meters.
Main Results:
- Without correction, significant waveform distortion (MSE > 0.001 L2/s2) was observed in ten waveforms with the Assess PEF meter.
- Correction reduced the mean MSE by 87.0% for these ten waveforms.
- Six waveforms showed distortion with the Micro DiaryCard meter; correction reduced their mean MSE by 58.4%.
Conclusions:
- The developed nonlinear model and gas compression compensation method effectively reduce distortion in pulmonary waveform generators.
- Accurate testing of respiratory function equipment, such as spirometers and PEF meters, is achievable with this correction technique.